Clozapine-Related Tachycardia: An Analysis of Incidence
Sinus tachycardia occurred in over two thirds of participants during the first month of clozapine titration. Spontaneous resolution of tachycardia in some suggests watchful monitoring may be appropriate prior to treatment with rate-controlling agents such as β-blockers or ivabradine. Long term follow-up is required to determine the effects of sinus tachycardia on cardiovascular outcomes in patients treated with clozapine.
Authors
- Dan J. Siskind (ORCID: https://orcid.org/0000-0002-2072-9216)
- Korinne Northwood (ORCID: https://orcid.org/0000-0001-6268-547X)
- Susanna Every‐Palmer (ORCID: https://orcid.org/0000-0001-6455-9741)
- James J. Tsakas
- Matthew K. Burrage (ORCID: https://orcid.org/0000-0003-3837-8140)
Institutions
- The University of Queensland (AU)
- Park Centre for Mental Health (AU)
- Royal Brisbane and Women's Hospital (AU)
- Metro South Health (AU)
- Ipswich Hospital (AU)
- Hutt Hospital (NZ)
- Queensland Centre for Mental Health Research (AU)
- University of Otago (NZ)
Publication Details
- Journal
- CNS Drugs
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1007/s40263-025-01177-5
- Citations
- 3
- Primary Topic
- Cardiovascular Syncope and Autonomic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- University of Queensland