Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection

RNApol3-associated myocarditis is an emerging disease linking autoimmunity and infection and a unique cause of acquired, pathogen-specific, organ-specific immunodeficiency. RNApol3 should be screened in all cases of FM, especially in young women infected by RNA viruses. The risk of FM in RNApol3-positive systemic sclerosis needs further investigation.

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Publication Details

Journal
Annals of Intensive Care
Published
2025-01-01
DOI
https://doi.org/10.1186/s13613-025-01443-1
Citations
1
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
1.39
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Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection

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Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection

David Levy, Alexis Mathian, Guillaume Hékimian, Isabelle Melki, Quentin Moyon, Christophe Parizot, Karim Dorgham, Philippe Rouvier, Ouriel Saura, Juliette Chommeloux, François Lifermann, Matthieu Petit, Charles‐Édouard Luyt, Guy Gorochov, Lucie Lefèvre, Paul Quentric, Alain Combes, Matthieu Schmidt, Marc Pineton de Chambrun, Mathieu Kernéis, Etienne Charpentier, Pierre Bay, Melchior Gautier, Omaira da Mata-Jardin, Sofia Ortuno, Zahir Amoura, Jean‐Luc Charuel, Karim Aacha
article en
1 citations

Abstract

RNApol3-associated myocarditis is an emerging disease linking autoimmunity and infection and a unique cause of acquired, pathogen-specific, organ-specific immunodeficiency. RNApol3 should be screened in all cases of FM, especially in young women infected by RNA viruses. The risk of FM in RNApol3-positive systemic sclerosis needs further investigation.

Annals of Intensive CareVol. 15(1)
Inserm (FR), Université Paris-Est Créteil (FR), Université Paris Cité (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Pitié-Salpêtrière Hospital (FR), Hôpital Robert-Debré (FR), Centre d'Immunologie et des Maladies Infectieuses (FR), Centre Hospitalier de Dax –Côte d’Argent (FR), Fondation pour l’innovation en Cadiométabolisme et Nutrition (FR)
Good health and well-being
Openalex Percentile: Top 21%
Viral Infections and Immunology Research
1.39
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