Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

TGFB1/MMP11 signaling contributes to the ALDH1A1-driven PCa metastases. MMP11 is a promising blood-based biomarker of PCa progression.

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Publication Details

Journal
Journal of Experimental & Clinical Cancer Research
Published
2025-03-23
DOI
https://doi.org/10.1186/s13046-025-03299-6
Citations
4
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
6.07

Funders

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article

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Ayşe Sedef Köseer, Mark Reardon, Tobias Hölscher, Łukasz Marczak et al.
4 citations
Journal of Experimental & Clinical Cancer Research
Prostate Cancer Treatment and Research
6.07
article

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Ayşe Sedef Köseer, Mark Reardon, Tobias Hölscher, Łukasz Marczak, Ielizaveta Gorodetska, Andrea Petzold, Mechthild Krause, Aldo Leal‐Egaña, Monika Pietrowska, Anna Dubrovska, Fabian Lohaus, Daria Klusa, Daniel Fochtman, Marta Gawin, Uğur Kahya, Piotr Wiland, Torsten Tonn, Vasyl Lukiyanchuk, Myroslava Y. Sliusar, Angelika Borkowetz, Claudia Peitzsch, Jakob Püschel, Annett Linge, Susanne Fuessel, Anna Wojakowska, Romy Kronstein‐Wiedemann, Kati Erdmann, Yasmin Antonelli, Christian Thomas, Ananya Choudhury
article en
4 citations

Abstract

TGFB1/MMP11 signaling contributes to the ALDH1A1-driven PCa metastases. MMP11 is a promising blood-based biomarker of PCa progression.

Journal of Experimental & Clinical Cancer ResearchVol. 44(1)
German Cancer Research Center (DE), Heidelberg University (DE), Helmholtz-Zentrum Dresden-Rossendorf (DE), German Red Cross (DE), University Hospital Heidelberg (DE), University of Manchester (GB), National Center for Tumor Diseases (DE), The Christie NHS Foundation Trust (GB), OncoRay (DE), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Institute of Bioorganic Chemistry, Polish Academy of Sciences (PL), University Hospital Carl Gustav Carus (DE), Deutsches Konsortium für Translationale Krebsforschung (DE), Gdańsk Medical University (PL)
Deutsche Forschungsgemeinschaft
Good health and well-being
Openalex Percentile: Top 4%
Prostate Cancer Treatment and Research
6.07
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