Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
TGFB1/MMP11 signaling contributes to the ALDH1A1-driven PCa metastases. MMP11 is a promising blood-based biomarker of PCa progression.
Authors
- Ayşe Sedef Köseer (ORCID: https://orcid.org/0000-0002-6733-9733)
- Mark Reardon (ORCID: https://orcid.org/0000-0001-5187-7038)
- Tobias Hölscher (ORCID: https://orcid.org/0000-0002-9991-6152)
- Łukasz Marczak (ORCID: https://orcid.org/0000-0001-8602-0077)
- Ielizaveta Gorodetska (ORCID: https://orcid.org/0000-0002-3512-0462)
- Andrea Petzold
- Mechthild Krause (ORCID: https://orcid.org/0000-0003-1776-9556)
- Aldo Leal‐Egaña (ORCID: https://orcid.org/0000-0002-8298-6525)
- Monika Pietrowska (ORCID: https://orcid.org/0000-0001-9317-7822)
- Anna Dubrovska (ORCID: https://orcid.org/0000-0002-3375-1500)
- Fabian Lohaus (ORCID: https://orcid.org/0000-0003-4043-7066)
- Daria Klusa
- Daniel Fochtman (ORCID: https://orcid.org/0000-0002-0754-7012)
- Marta Gawin (ORCID: https://orcid.org/0000-0002-2834-5129)
- Uğur Kahya (ORCID: https://orcid.org/0000-0002-3708-8806)
- Piotr Wiland (ORCID: https://orcid.org/0000-0001-9999-0267)
- Torsten Tonn (ORCID: https://orcid.org/0000-0001-9580-2193)
- Vasyl Lukiyanchuk
- Myroslava Y. Sliusar (ORCID: https://orcid.org/0000-0003-3296-1482)
- Angelika Borkowetz (ORCID: https://orcid.org/0000-0001-7257-0238)
- Claudia Peitzsch (ORCID: https://orcid.org/0000-0002-5247-908X)
- Jakob Püschel
- Annett Linge (ORCID: https://orcid.org/0000-0001-9636-1721)
- Susanne Fuessel (ORCID: https://orcid.org/0000-0002-5339-9460)
- Anna Wojakowska (ORCID: https://orcid.org/0000-0002-4541-1239)
- Romy Kronstein‐Wiedemann (ORCID: https://orcid.org/0000-0001-7329-3711)
- Kati Erdmann (ORCID: https://orcid.org/0000-0003-3717-3637)
- Yasmin Antonelli (ORCID: https://orcid.org/0009-0008-0336-2660)
- Christian Thomas (ORCID: https://orcid.org/0000-0001-6511-965X)
- Ananya Choudhury
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- German Red Cross (DE)
- University Hospital Heidelberg (DE)
- University of Manchester (GB)
- National Center for Tumor Diseases (DE)
- The Christie NHS Foundation Trust (GB)
- OncoRay (DE)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Institute of Bioorganic Chemistry, Polish Academy of Sciences (PL)
- University Hospital Carl Gustav Carus (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1186/s13046-025-03299-6
- Citations
- 4
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 6.07
Funders
- Deutsche Forschungsgemeinschaft