An Autopsy Case of Bronchiolitis Obliterans Associated With Oral Lichen Planus and Non-Hodgkin Lymphoma

We report the autopsy case of a 66-year-old woman with indolent B-cell non-Hodgkin lymphoma (NHL) who underwent repeated chemotherapy for 18 years. Two and a half years ago, she developed oral lichen planus and began corticosteroid treatment. Lichen planus recurred repeatedly with corticosteroid reduction. Obstructive ventilation impairment and respiratory failure had progressed two years ago. She was admitted to the hospital due to cytomegalovirus infection and died of respiratory failure. An autopsy revealed bronchiolitis obliterans, oral lichen planus, and recurrence of pre-existing NHL. This was a rare case of bronchiolitis obliterans with oral lichen planus and NHL.

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Publication Details

Journal
Cureus
Published
2025-03-23
DOI
https://doi.org/10.7759/cureus.81048
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
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article

An Autopsy Case of Bronchiolitis Obliterans Associated With Oral Lichen Planus and Non-Hodgkin Lymphoma

Hideki Hashidate, Hiroki Tsukada, Toshiaki Kikuchi, Kenji Kurashina et al.
Cureus
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

An Autopsy Case of Bronchiolitis Obliterans Associated With Oral Lichen Planus and Non-Hodgkin Lymphoma

Hideki Hashidate, Hiroki Tsukada, Toshiaki Kikuchi, Kenji Kurashina, Satoshi Hokari, Takeshi Koizumi, Satoshi Shibata, Katsuhiro Tomiyama
article en

Abstract

We report the autopsy case of a 66-year-old woman with indolent B-cell non-Hodgkin lymphoma (NHL) who underwent repeated chemotherapy for 18 years. Two and a half years ago, she developed oral lichen planus and began corticosteroid treatment. Lichen planus recurred repeatedly with corticosteroid reduction. Obstructive ventilation impairment and respiratory failure had progressed two years ago. She was admitted to the hospital due to cytomegalovirus infection and died of respiratory failure. An autopsy revealed bronchiolitis obliterans, oral lichen planus, and recurrence of pre-existing NHL. This was a rare case of bronchiolitis obliterans with oral lichen planus and NHL.

CureusVol. 17(3)
Niigata City General Hospital (JP), Saiseikai Niigata Daini Hospital (JP), Niigata University Medical and Dental Hospital (JP), Jikei University Kashiwa hospital (JP), Nippon Life Hospital (JP), Niigata University (JP)
Zero hunger
Openalex Percentile: Top 92%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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