Antigen-driven expansion of public clonal T-cell populations in inflammatory bowel diseases

There are peptide antigens that commonly evoke immune reactions in IBD cases and rarely in non-IBD controls. These antigens differ between CD and UC. CD, particularly ileal CD, also seems to involve more substantial changes in clonal population structure than UC, compared to HCs.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2025-03-13
DOI
https://doi.org/10.1093/ecco-jcc/jjaf048
Citations
13
Primary Topic
T-cell and B-cell Immunology
Type
article
Field-Weighted Citation Impact
10.37
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article

Antigen-driven expansion of public clonal T-cell populations in inflammatory bowel diseases

Ian M. Kaplan, Harlan Robins, Damon May, Wenyu Zhou et al.
13 citations
Journal of Crohn s and Colitis
T-cell and B-cell Immunology
10.37
article

Antigen-driven expansion of public clonal T-cell populations in inflammatory bowel diseases

Ian M. Kaplan, Harlan Robins, Damon May, Wenyu Zhou, Matthieu Allez, Ramit Bharanikumar, H. Jabran Zahid, Bernd Bokemeyer, Rachel M. Gittelman, Thomas M. Snyder, Haiyin Chen‐Harris, Elisa Rosati, Julia Greissl, Cara L. Carty, Mitchell W. Pesesky, Hesham ElAbd, Jennifer N. Dines, Marco Garcia Noceda, Namita Singh, Stefan Schreiber, Lionel Le Bourhis, Paidamoyo Chapfuwa, Bryan Howie, Andre Franke, Siegfried Görg
article en
13 citations

Abstract

There are peptide antigens that commonly evoke immune reactions in IBD cases and rarely in non-IBD controls. These antigens differ between CD and UC. CD, particularly ileal CD, also seems to involve more substantial changes in clonal population structure than UC, compared to HCs.

Journal of Crohn s and ColitisVol. 19(7)
Microsoft (United States) (US), Inserm (FR), Université Paris Cité (FR), Institute for Transfusion Medicine (US), Sorbonne Paris Cité (FR), Assistance Publique – Hôpitaux de Paris (FR), Adaptive Biotechnologies (United States) (US), University Hospital Schleswig-Holstein (DE), Hôpital Lariboisière (FR), Institut Cochin (FR), Hôpital Saint-Louis (FR), Institut de recherche Saint-Louis (FR), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 1%
T-cell and B-cell Immunology
10.37
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