Radiomic features of infrapatellar fat pad are associated with knee symptoms and radiographic post-traumatic osteoarthritis at 10+ years after anterior cruciate ligament reconstruction
Radiomics features describing IPFP intensity, morphology, and texture achieve fair to moderate performance in discriminating PTOA-positive from PTOA-negative patients, defined either symptomatically or radiographically. These features describe the relationship between the IPFP and PTOA and are candidates for prognostic models or diagnostic scores that would link knee imaging to patient symptoms.
Authors
- Brendan Eck (ORCID: https://orcid.org/0000-0003-0971-4432)
- Michael Knopp
- Laura J. Huston (ORCID: https://orcid.org/0000-0002-9901-7165)
- Jeehun Kim (ORCID: https://orcid.org/0000-0001-7985-5519)
- Mei Li (ORCID: https://orcid.org/0000-0003-3915-4210)
- Sameed Khan (ORCID: https://orcid.org/0000-0002-9034-7563)
- Christopher C. Kaeding (ORCID: https://orcid.org/0000-0002-5540-0875)
- Kurt P. Spindler (ORCID: https://orcid.org/0000-0002-0185-6922)
- Richard Lartey (ORCID: https://orcid.org/0000-0002-8336-7363)
- Sibaji Gaj (ORCID: https://orcid.org/0000-0002-6997-5717)
- Faysal Altahawi
- Kevin D. Harkins (ORCID: https://orcid.org/0000-0003-3579-9273)
- Carl S. Winalski (ORCID: https://orcid.org/0000-0002-1101-0402)
- Morgan H. Jones (ORCID: https://orcid.org/0000-0002-5466-0624)
- Nancy A. Obuchowski (ORCID: https://orcid.org/0000-0003-1891-7477)
- Xiaojuan Li (ORCID: https://orcid.org/0000-0002-1305-0846)
Institutions
- Brigham and Women's Hospital (US)
- Cleveland Clinic (US)
- The Ohio State University Wexner Medical Center (US)
- Cleveland Clinic Lerner College of Medicine (US)
- The Ohio State University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Osteoarthritis Imaging
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1016/j.ostima.2025.100263
- Citations
- 2
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Arthritis Foundation
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases