Physicochemical stability of a polysorbate-80-containing solvent compounded in the hospital pharmacy and used to reconstitute a biologic for nebulisation
A PS80-containing solvent is stable for 1 year when stored at -20°C (±5°C) in amber glass vials. Moreover, the solvent is stable for up to 1 month after thawing if stored at 2-8°C.
Authors
- Marine Roche
- Antoine Guillon (ORCID: https://orcid.org/0000-0002-4884-8620)
- Christophe Berneron
- Christophe Carnoy (ORCID: https://orcid.org/0000-0003-2047-5153)
- Jean-Claude Sirard
- Laura Négrier (ORCID: https://orcid.org/0000-0001-9879-5347)
- B. Hamzé
- Bertrand Décaudin (ORCID: https://orcid.org/0000-0001-8267-5594)
- Damien Lannoy (ORCID: https://orcid.org/0000-0002-4657-0282)
- Cécile Danel (ORCID: https://orcid.org/0000-0002-8960-0496)
- Pascal Odou (ORCID: https://orcid.org/0000-0003-1555-6530)
- Léa Pacqueu
Institutions
- Université de Tours (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Lille (FR)
- Institut Pasteur de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Center for Infection and Immunity of Lille (FR)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1136/ejhpharm-2024-004441
- Primary Topic
- Safe Handling of Antineoplastic Drugs
- Type
- article
- Field-Weighted Citation Impact
- 0.00