Impact of pre-existing immunity on humoral and cellular responses to CoronaVac in SARS-CoV-2 variants: A focus on common human Coronaviruses
This work demonstrate that CoronaVac induces robust humoral and cellular immune responses, though variant-specific responses vary. Pre-existing immunity to certain HCoVs may influence vaccine-induced antibody responses, underscoring the importance of monitoring immunity to emerging SARS-CoV-2 variants and informing future vaccine design.
Authors
- Ratchanon Sophonmanee (ORCID: https://orcid.org/0009-0009-3431-6576)
- Jomkwan Ongarj
- Bunya Seeyankem
- Smonrapat Surasombatpattana (ORCID: https://orcid.org/0000-0003-1447-5114)
- Nawamin Pinpathomrat (ORCID: https://orcid.org/0000-0002-0776-595X)
Institutions
- Prince of Songkla University (TH)
Publication Details
- Journal
- Asian Pacific Journal of Allergy and Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.12932/ap-201124-1979
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Prince of Songkla University
- National Research Council of Thailand
- Faculty of Medicine, Prince of Songkla University