KLF2 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Regulating Nrf2 Expression
The findings of the study demonstrate KLF2 overexpression has the ability to promote the osteogenic differentiation of hPDLSCs by promoting Nrf2 activation, suggesting that KLF2 mediating Nrf2 could be a promising target to facilitate the efficacy of PDLSC-based bone regeneration in periodontitis.
Authors
- Lichao Deng
- Jixin Chen (ORCID: https://orcid.org/0000-0003-3309-1685)
Institutions
- Wenzhou Medical University (CN)
- Wenzhou Central Hospital (CN)
- Stomatology Hospital (CN)
- Wenzhou City People's Hospital (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1016/j.identj.2025.02.019
- Citations
- 5
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 4.03