140P Prognostic factors for early recurrence in synovial sarcoma of the extremities

Synovial sarcoma (SS) is a rare subtype of soft tissue sarcoma (STS), representing 5–10% of all STS cases. Typically presents at a younger mean age (39 years) and occurs equally in both sexes. Most cases arise in the extremities. While wide surgical excision remains the mainstay of treatment, the role of chemotherapy is controversial, and radiotherapy is often used for larger, deeper lesions. Factors such as tumor size, grade, and patient age have been associated with worse outcomes, but evidence is limited regarding early recurrence predictors.

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Publication Details

Journal
ESMO Open
Published
2025-03-01
DOI
https://doi.org/10.1016/j.esmoop.2025.104453
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

140P Prognostic factors for early recurrence in synovial sarcoma of the extremities

Sylvia Veronica Villavicencio-Valencia, Caro Cebrián C, Ana Paulina Meléndez-Fernández, Dorian Yarih García-Ortega et al.
ESMO Open
Sarcoma Diagnosis and Treatment
article

140P Prognostic factors for early recurrence in synovial sarcoma of the extremities

Sylvia Veronica Villavicencio-Valencia, Caro Cebrián C, Ana Paulina Meléndez-Fernández, Dorian Yarih García-Ortega, Gabriela Alamilla-García, K.F. Reyna, Diyitzia Rosario Irineo-Cerecedo
article en

Abstract

Synovial sarcoma (SS) is a rare subtype of soft tissue sarcoma (STS), representing 5–10% of all STS cases. Typically presents at a younger mean age (39 years) and occurs equally in both sexes. Most cases arise in the extremities. While wide surgical excision remains the mainstay of treatment, the role of chemotherapy is controversial, and radiotherapy is often used for larger, deeper lesions. Factors such as tumor size, grade, and patient age have been associated with worse outcomes, but evidence is limited regarding early recurrence predictors.

ESMO OpenVol. 10
Instituto Nacional de Cancerología (MX)
Openalex Percentile: Top 92%
Sarcoma Diagnosis and Treatment
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