Leucine-rich α-2 glycoprotein 1 (LRG1) during inflammatory complications after allogeneic stem cell transplantation and CAR-T cell therapy

The current data support the hypothesis that LRG1 is an attractive therapeutic target after alloHSCT and after CAR-T cell therapy for cancer because of its role in dysfunctional tumor vessels as well as in inflammatory complications.

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Publication Details

Journal
Journal for ImmunoTherapy of Cancer
Published
2025-03-01
DOI
https://doi.org/10.1136/jitc-2024-009372
Citations
1
Primary Topic
Clusterin in disease pathology
Type
article
Field-Weighted Citation Impact
1.05

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article

Leucine-rich α-2 glycoprotein 1 (LRG1) during inflammatory complications after allogeneic stem cell transplantation and CAR-T cell therapy

Katarina Riesner, John Pierre Greenwood, Hadeer Mohamed Rasheed, Lars Bullinger et al.
1 citations
Journal for ImmunoTherapy of Cancer
Clusterin in disease pathology
1.05
article

Leucine-rich α-2 glycoprotein 1 (LRG1) during inflammatory complications after allogeneic stem cell transplantation and CAR-T cell therapy

Katarina Riesner, John Pierre Greenwood, Hadeer Mohamed Rasheed, Lars Bullinger, Ningyu Li, Pedro Vallecillo-García, Jerome Jatzlau, Martina Kalupa, Stephen E. Moss, Olaf Penack, Petra Knaus, Sarah Mertlitz, Lydia Verlaat, Steffen Cordes, Mina Jamali, Nora Uhlig
article en
1 citations

Abstract

The current data support the hypothesis that LRG1 is an attractive therapeutic target after alloHSCT and after CAR-T cell therapy for cancer because of its role in dysfunctional tumor vessels as well as in inflammatory complications.

Journal for ImmunoTherapy of CancerVol. 13(3)
Humboldt-Universität zu Berlin (DE), National Center for Tumor Diseases (DE), German Marine Research Consortium (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Deutsches Konsortium für Translationale Krebsforschung (DE), University College London (GB), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Deutsche Forschungsgemeinschaft, José Carreras Leukämie-Stiftung, Deutsche Krebshilfe, Stiftung Charité
Good health and well-being
Openalex Percentile: Top 24%
Clusterin in disease pathology
1.05
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