Size and Contrast Thresholds for Liver Lesion Detection in Regular and Low-dose CT Examinations: A Reader Study of 2300 Synthetic Lesions Across 100 Patients
In oncologic CT examinations, liver lesions with diameters of 15-, 10-, and 5-mm require contrasts of -30, -35, and -70 HU, respectively for reliable detection. In low-dose examinations, greater contrasts of -40 and -50 HU are required for lesions measuring 15- and 10-mm, while readers do not reliably detect 5-mm lesions.
Authors
- Bernd Hamm (ORCID: https://orcid.org/0000-0002-9141-027X)
- Ulrich Genske (ORCID: https://orcid.org/0000-0003-2462-5163)
- Antonino Laudani (ORCID: https://orcid.org/0000-0001-9655-3504)
- Katharina Beller
- Thula Walter (ORCID: https://orcid.org/0000-0002-2003-8351)
- Paul Jahnke (ORCID: https://orcid.org/0000-0003-2039-6316)
- Yan Li (ORCID: https://orcid.org/0009-0000-1331-9182)
- Yang Peng (ORCID: https://orcid.org/0009-0003-2824-5843)
- Moritz Wagner (ORCID: https://orcid.org/0000-0002-5045-1374)
Institutions
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Academic Radiology
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1016/j.acra.2025.03.001
- Citations
- 1
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.67