EGFR-mediated local invasiveness and response to Cetuximab in head and neck cancer
We describe an actionable network of EGFR-mediated local invasion and define druggable effectors with predictive potential regarding the response of R/M-HNSCC to Cetuximab.
Authors
- Melanie Boxberg (ORCID: https://orcid.org/0000-0001-5989-7922)
- Iordanis Ourailidis (ORCID: https://orcid.org/0000-0001-6783-5617)
- Claus Belka (ORCID: https://orcid.org/0000-0002-1287-7825)
- Jiahang Song (ORCID: https://orcid.org/0000-0001-7858-2096)
- Zhengquan Wu (ORCID: https://orcid.org/0000-0002-8302-4424)
- Jiefu Zhou (ORCID: https://orcid.org/0000-0001-6340-7498)
- Kristian Unger (ORCID: https://orcid.org/0000-0002-0374-2320)
- Olivier Gires (ORCID: https://orcid.org/0000-0002-2292-7064)
- Horst Zitzelsberger (ORCID: https://orcid.org/0000-0002-5411-9213)
- Philipp Baumeister (ORCID: https://orcid.org/0000-0003-2759-4737)
- Enxian Shi
- Andreas Möck (ORCID: https://orcid.org/0000-0002-3332-9166)
- Dongmei Ji (ORCID: https://orcid.org/0000-0003-0647-0153)
- Sabina Schwenk‐Zieger
- Fabian Stögbauer (ORCID: https://orcid.org/0000-0002-8897-5165)
- Julia Heß (ORCID: https://orcid.org/0000-0001-9860-1426)
- Gisela Kranz
- Jan Budczies (ORCID: https://orcid.org/0000-0002-6668-5327)
- Hongxia Wang (ORCID: https://orcid.org/0000-0002-3269-5770)
- Qiong Zhao (ORCID: https://orcid.org/0000-0002-6349-1682)
- Hairong Wang (ORCID: https://orcid.org/0009-0003-6835-0998)
- Min He (ORCID: https://orcid.org/0000-0002-5497-1385)
- Christoph Andreas Reichel (ORCID: https://orcid.org/0000-0003-2145-0388)
- Martin Canis
- Nilofer Abdul Razak
- Anna Tscherne
- Vaidehi Ponkshe
Institutions
- Central South University (CN)
- Sun Yat-sen University (CN)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- Fudan University Shanghai Cancer Center (CN)
- Comprehensive Cancer Center Mainfranken (DE)
- Soil and Fertilizer Institute of Hunan Province (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Xiangya Hospital Central South University (CN)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1186/s12943-025-02290-1
- Citations
- 12
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 12.54