Seroprevalence of Igg Antibodies against Herpes Simplex Virus 1 and 2 in Children Born HIV Positive under Antiretroviral Treatment at the Yaounde University Teaching Hospital

Background: Infection with the Human Immunodeficiency Virus (HIV) is responsible for the terminal stage of Acquired Immunodeficiency Syndrome (AIDS), which was a latent infection until the introduction of antiretroviral treatment. The progression to chronicity of this infection leads to chronic inflammation that facilitates the occurrence of opportunistic infections such as herpes simplex virus types 1 and 2 (Herpes Simplex Virus-1 (HSV-1) and Herpes Simplex Virus-2 (HSV-2). The lack of data on these viruses has led to the present study, which aimed to determine the seroprevalence of IgG antibodies against herpes simplex virus types 1 and 2 in children born HIV-positive to HIV-positive mothers with an undetectable viral load and receiving antiretroviral treatment at the Yaoundé University Teaching Hospital (YUTH).