The critical role of platelet adenylyl cyclase 6 in hemostasis and thrombosis
These data demonstrate that AC6 is linked directly to PGI<sub>2</sub>-mediated platelet inhibition and regulation of hemostasis and thrombosis in vivo.
Authors
- Beth A. Webb (ORCID: https://orcid.org/0000-0001-9075-8250)
- Robert A.S. Ariëns (ORCID: https://orcid.org/0000-0002-6310-5745)
- Niall Turner (ORCID: https://orcid.org/0000-0003-1004-2952)
- Mark T. Kearney (ORCID: https://orcid.org/0000-0002-9376-8814)
- Jawad S. Khalil (ORCID: https://orcid.org/0000-0002-1408-9523)
- Khalid M. Naseem (ORCID: https://orcid.org/0000-0002-3870-8747)
- Matthew S. Hindle (ORCID: https://orcid.org/0000-0002-5633-2034)
- Cédric Duval (ORCID: https://orcid.org/0000-0002-4870-6542)
- M. Craig McKay
- Lih T. Cheah (ORCID: https://orcid.org/0000-0002-2805-9931)
Institutions
- University of Leeds (GB)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1016/j.jtha.2025.02.045
- Citations
- 3
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.31
Funders
- British Heart Foundation
- University of Leeds