Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation
We evaluated the anti-accelerated epidermal skin aging effects of compound K (CK) on keratinocytes using IL-17A and ultraviolet B. CK restored epidermal functions and reduced the induction of pro-inflammatory cytokines by inhibiting NF-κB and p38 MAPK activation. CK plays a significant role in controlling accelerated epidermal skin aging.
Authors
- Ji-Yong Jung
- Jae Hee Cho (ORCID: https://orcid.org/0000-0003-4174-0091)
- Si‐Young Cho (ORCID: https://orcid.org/0000-0002-0403-5599)
- Donghyun Kim (ORCID: https://orcid.org/0000-0003-1960-0527)
- Yong Deog Hong
- Hyoung-June Kim
- A. Kim
Institutions
- Amorepacific (South Korea) (KR)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1016/j.jgr.2025.03.004
- Citations
- 1
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.80