Radiomics to predict tumor response to combination chemoradiotherapy in squamous cell carcinoma of the anal canal: a preliminary investigation
A non-negligible fraction of patients with anal SCC respond unsatisfactorily to CRT. Our radiomic model predicted response to CRT based on pretreatment MRI. We observed a more homogeneous tissue composition in poor responders. The slow proliferation of a dominant clone may explain non-CR to CRT.
Authors
- Riccardo Lattanzi (ORCID: https://orcid.org/0000-0002-8240-5903)
- S. Villà (ORCID: https://orcid.org/0000-0002-8034-2603)
- Filippo Patti (ORCID: https://orcid.org/0000-0001-6747-7645)
- Laura Lozza (ORCID: https://orcid.org/0000-0002-7413-7427)
- Davide Scaramuzza (ORCID: https://orcid.org/0000-0002-4798-5682)
- Lucilla Violetta Sciacqua (ORCID: https://orcid.org/0000-0003-1774-0729)
- Eros Montin (ORCID: https://orcid.org/0000-0002-1773-0064)
- Andrea Vanzulli (ORCID: https://orcid.org/0000-0001-6281-7807)
- Roza Drebot
Institutions
- Humanitas University (IT)
- University of Milan (IT)
- Advanced Imaging Research (United States) (US)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- New York University (US)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1186/s41747-025-00559-0
- Citations
- 2
- Primary Topic
- Colorectal and Anal Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 4.01