31P A global examination of clinical trials for patients with salivary gland cancers: An in-depth review of international registries and current challenges

Clinical trials (CTs) are crucial for improving the level of scientific evidence and clinical outcomes, but can be challenging in rare subtypes of cancers. Salivary Gland Cancers (SGC) are rare and highly heterogenic tumours, lacking approved systemic therapies and good responses. Their rarity and usual absence of centralized management significantly reduces the chances to develop CTs. We performed a descriptive analysis of SGC CTs to map the landscape of CT activity for patients with SGC.

Authors

Institutions

Publication Details

Journal
ESMO Open
Published
2025-03-01
DOI
https://doi.org/10.1016/j.esmoop.2025.104341
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

31P A global examination of clinical trials for patients with salivary gland cancers: An in-depth review of international registries and current challenges

Robert L. Metcalf, Ben O’Leary, Pablo Jiménez Labaig, M.D. Forster et al.
ESMO Open
Salivary Gland Tumors Diagnosis and Treatment
article

31P A global examination of clinical trials for patients with salivary gland cancers: An in-depth review of international registries and current challenges

Robert L. Metcalf, Ben O’Leary, Pablo Jiménez Labaig, M.D. Forster, L. Lorini, Cristina Gurizzan, P. Bossi, Kevin Joseph Harrington, E. Kinloch, Irene Braña, Enriqueta Felip, Renata Ferrarotto, Shelley Burton, G.J. Hanna
article en

Abstract

Clinical trials (CTs) are crucial for improving the level of scientific evidence and clinical outcomes, but can be challenging in rare subtypes of cancers. Salivary Gland Cancers (SGC) are rare and highly heterogenic tumours, lacking approved systemic therapies and good responses. Their rarity and usual absence of centralized management significantly reduces the chances to develop CTs. We performed a descriptive analysis of SGC CTs to map the landscape of CT activity for patients with SGC.

ESMO OpenVol. 10
The University of Texas MD Anderson Cancer Center (US), Institute of Cancer Research (GB), Royal Hospital Chelsea (GB), London International Development Centre (GB), London Cancer (GB), Dana-Farber Cancer Institute (US), Royal Marsden Hospital (GB), Vall d'Hebron Hospital Universitari (ES), The Christie NHS Foundation Trust (GB), UCL Biomedical Research Centre (GB), IRCCS Humanitas Research Hospital (IT), University College London (GB)
Partnerships for the goals
Openalex Percentile: Top 91%
Salivary Gland Tumors Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.