Investigation of changes in planning target volume and regression probability of rectal boost using in-silico cone-beam computed tomography-guided online-adaptive radiotherapy
Online-ART significantly reduce rectal boost PTV margin. It allows better target volume coverage with a similar risk of radiation-induced toxicities, even when escalating the dose. Therefore, online-ART should be considered to perform dose-escalation in LARC patients with the objective of organ preservation.
Authors
- Geneviève Van Ooteghem
- David Dechambre (ORCID: https://orcid.org/0000-0002-8038-4889)
- Julien Pierrard (ORCID: https://orcid.org/0000-0003-0880-9894)
Institutions
- Cliniques Universitaires Saint-Luc (BE)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1016/j.phro.2025.100757
- Citations
- 1
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Fonds De La Recherche Scientifique - FNRS
- Siemens Healthineers