Bariatric surgery as a potential trigger for worsening hereditary spastic paraparesis: Case report
We report a patient with c.1246C>T (p.R416C) heterozygous variant on the ATL1 gene causing a complicated form of hereditary spastic paraparesis (HSP) who had an early age of onset but had non-progressive disease until a rapid decline at age 57 after bariatric surgery. To our knowledge, there have been no studies or case reports documenting a trigger for clinical worsening in patients with HSP.
Authors
- Hristelina Ilieva (ORCID: https://orcid.org/0000-0001-8318-7533)
- Rebecca Hsu (ORCID: https://orcid.org/0000-0001-6158-0561)
Institutions
- Thomas Jefferson University Hospital (US)
- California University of Pennsylvania (US)
Publication Details
- Journal
- RRNMF Neuromuscular Journal
- Published
- 2025-03-22
- DOI
- https://doi.org/10.17161/rrnmf.v6i1.22493
- Primary Topic
- Hereditary Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00