Anti-interleukin-5 efficacy in an inclisiran-triggered eosinophilic myocarditis: a case report
This case describes an uncommon response to inclisiran that resulted in <i>Aspergillus</i>-induced, steroid-dependent, eosinophilic systemic inflammation, resulting in severe asthma and endocarditis. It demonstrates how biological IL-5 inhibitors are effective in treating both components, emphasizing the necessity of a multidisciplinary strategy.
Authors
- Cristina Panico (ORCID: https://orcid.org/0000-0002-9198-3676)
- Maria Messina (ORCID: https://orcid.org/0000-0003-3999-3372)
- Enrico Marco Heffler (ORCID: https://orcid.org/0000-0002-0492-5663)
- Stefania Rizzo (ORCID: https://orcid.org/0000-0002-8575-1748)
- Francesco Tartaglia
Institutions
- Humanitas University (IT)
- University of Padua (IT)
- Mylan (Switzerland) (CH)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-03-16
- DOI
- https://doi.org/10.1093/ehjcr/ytaf127
- Citations
- 3
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 5.00