Morphine self-administration decreases intrinsic excitability of accumbal medium spiny neurons and suppresses the innate immune system in male Wistar rats
The data presented here demonstrates that morphine self-administration produces accumbal neuroplasticity and biological transformations that could contribute to the addictive and immunosuppressive properties of morphine.
Authors
- Klara Danielsson (ORCID: https://orcid.org/0000-0001-6229-7178)
- Mia Ericson (ORCID: https://orcid.org/0000-0002-7557-7109)
- Bo Söderpalm (ORCID: https://orcid.org/0000-0001-9434-6878)
- Erika Lucente (ORCID: https://orcid.org/0009-0007-4152-9663)
- Louise Adermark (ORCID: https://orcid.org/0000-0002-7165-9908)
- Davide Cadeddu
Institutions
- Sahlgrenska University Hospital (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Neurochemistry International
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1016/j.neuint.2025.105965
- Citations
- 2
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Vetenskapsrådet