Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma

Collectively, our analysis demonstrated the metabolic heterogeneity of HCCs and enabled the development of clinical translation strategies, thus promoting understanding and clinical applications about HCC metabolism heterogeneity.

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Publication Details

Journal
Journal of Translational Medicine
Published
2025-03-22
DOI
https://doi.org/10.1186/s12967-025-06347-z
Citations
4
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
3.75
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article

Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma

Xiang-Yu Gan, Jinshu Pang, Yun He, Hong Yang et al.
4 citations
Journal of Translational Medicine
Cancer, Hypoxia, and Metabolism
3.75
article

Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma

Xiang-Yu Gan, Jinshu Pang, Yun He, Hong Yang, Peng Lin, Rong Wen, Qiong Qin
article en
4 citations

Abstract

Collectively, our analysis demonstrated the metabolic heterogeneity of HCCs and enabled the development of clinical translation strategies, thus promoting understanding and clinical applications about HCC metabolism heterogeneity.

Journal of Translational MedicineVol. 23(1)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Zero hunger
Openalex Percentile: Top 7%
Cancer, Hypoxia, and Metabolism
3.75
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Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma — Xiang-Yu Gan, Jinshu Pang, et al. · Journal of Translational Medicine (2025) | TGRS Research Map | TGRS