From Fins to Furs: Unlocking the Therapeutic Potential of Animal-derived Bioactives for Wound Care
Animal-derived products, such as organs, secretions, and mucus, have been part and parcel of traditional medicine and are often overlooked in the modern healthcare system. Nevertheless, researchers have begun to explore the untapped potential of bioactive compounds from marine organisms, reptiles, amphibians, and insects, thus offering innovative solutions for wound care. This review delved into the medicinal properties of animal-based bioactive compounds in wound healing based on in vitro and in vivo studies. A comparative analysis of the empirical evidence was performed to determine the benefits and limitations of animal-derived bioactive compounds. In summary, the literature suggests that animal-derived products could regulate biological pathways involved in inflammation and tissue regeneration. Clinical trials are underway to affirm the feasibility and safety of these compounds for human health applications.
Authors
- Eng Hwa Wong (ORCID: https://orcid.org/0000-0001-9322-772X)
- Christopher J. Serpell (ORCID: https://orcid.org/0000-0002-2848-9077)
- Yong Hu (ORCID: https://orcid.org/0000-0003-0305-5616)
- Satoshi Ogawa (ORCID: https://orcid.org/0000-0001-6664-4448)
- Hui Sin Lim
Institutions
- Monash University Malaysia (MY)
- Royal Pharmaceutical Society (GB)
- Taylor's University (MY)
- University College London (GB)
Publication Details
- Journal
- Medicine in Drug Discovery
- Published
- 2025-03-23
- DOI
- https://doi.org/10.1016/j.medidd.2025.100206
- Primary Topic
- Insect Utilization and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00