THE MOLECULAR BIOLOGICAL INVESTIGATION OF ACHILLEA MILLEFOLIUM (YARROW) EXTRACT ON SACCHAROMYCES CEREVISIAE

Yarrow, whose scientific name is "Achillea millefolium", is a flowering plant belonging to the Asteraceae family. Almost all parts of Achillea millefolium, a perennial herbaceous plant, are medically useful. It has many bioactive features such as anti-inflammatory, anti-spasmodic, analgesic, blood coagulant, wound healing, anti-hypertension, expectorant and menstrual regulator. Today, Covid-19, caused by severe acute respiratory syndrome, has brought about some studies on using natural therapeutics along with researching drug treatment, as well as developing a vaccine. For this reason, by investigating the natural therapeutic effect of the Achillea millefolium extract that we will use in our study, studies on its use as an alternative medicine in Covid-19 will be accelerated. This study aims to examine the protective effects of Achillea millefolium plant extract against changes at the cellular level. After the addition of carbon tetrachloride and Achillea millefolium extracts, the cultures were allowed to develop at 30°C. It was determined that oxidative stress and lipid peroxidation decreased and catalase and glutathione levels, which are anti-oxidant defense markers, increased after treatment with Achillea millefolium extracts. Based on these findings, it can be concluded that Achillea millefolium has beneficial properties in protecting the cell against oxidative damage.