Efficiency of Cynara Cornigera Fruits on Antibacterial, Antifungal and Its Phytochemical, Anti-Oxidant Screening

The Cynara Cornigera is one of the most plants growing naturally in many of Libyan areas. Its fruits were widely consumed due to interesting taste, so the local population used it in a variety of medical applications. In this the Cynara Cornigera fruits were selected to investigate the efficiency of some extracts (aqueous and alcohol) against Gram-positive bacteria of (Staphylococcus aureus, Bacillus cereus, and Streptococcus pneumonia) and Gram-negative (Escherichia coli and Proteus vulgaris), besides some fungal specie including Aspergilla's niger., also the phytochemical, total phenols and antioxidant activities were detected. The results recorded that the plant fruits containing many natural product constituents such as carbohydrates and/or glycosides, flavonoids, sterols and/or triterpenes, and cardiac glycoside, there are small variations of their contents in aqueous and alcoholic extracts. For the antibacterial activities, higher concentrations of extracts of (0.1 – 0.8 g/ 100 ml) showed high effects compared with lower ones of (0.0001 – 0.1 g/ 100 ml) against the selected bacteria in this study. The contents of total phenols were 648.61 and 178.5 mg/ml in Alcohol and aqueous extracts, respectively, while the anti- oxidant capacity was 45.20 mg/ml. The study concluded that the presence of natural product compounds mainly the main reason for the inhibition of bacteria and the different effects were attributed to the effect of solvent polarizes during the extraction