Long-term outcomes of intraventricular baclofen therapy for medically refractory generalized secondary dystonia

IVB is well tolerated in patients with generalized secondary dystonia refractory to conventional medical therapy, ITB, and deep brain stimulation. Positive long-term outcomes were reported in this cohort, with significant improvement in dystonia and overall complication rates similar to those reported with ITB.

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Publication Details

Journal
Journal of Neurosurgery Pediatrics
Published
2025-03-22
DOI
https://doi.org/10.3171/2024.12.peds24418
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-term outcomes of intraventricular baclofen therapy for medically refractory generalized secondary dystonia

Emily J. Meyer, Joyce Koueik, Brandon G. Rocque, A. Leland Albright et al.
Journal of Neurosurgery Pediatrics
Botulinum Toxin and Related Neurological Disorders
article

Long-term outcomes of intraventricular baclofen therapy for medically refractory generalized secondary dystonia

Emily J. Meyer, Joyce Koueik, Brandon G. Rocque, A. Leland Albright, Tenzing Lhamo, Susan Hubanks
article en

Abstract

IVB is well tolerated in patients with generalized secondary dystonia refractory to conventional medical therapy, ITB, and deep brain stimulation. Positive long-term outcomes were reported in this cohort, with significant improvement in dystonia and overall complication rates similar to those reported with ITB.

Journal of Neurosurgery PediatricsVol. 35(5)
University of Wisconsin–Madison (US), Children's of Alabama (US), University of Alabama at Birmingham (US), Neurological Surgery (US)
Good health and well-being
Openalex Percentile: Top 91%
Botulinum Toxin and Related Neurological Disorders
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