Etiology and Perinatal Outcome of Polyhydramnios: An Experience of Tertiary Center

Aim: To review our experience in fetuses with prenatally diagnosed with polyhydramniosis Materials and Method: Retrospective study of fetuses prenatally diagnosed with polyhydramniosis between October 2023 and January 2025 in a tertiary referral center. Results: 104 pregnant women were included in the final analysis. When we classify the cases according to etiology of polyhydramnios, 31 (29.8 %) women had pregestational or gestational diabetes, in 8 (7.6 %) infants major structural or significant genetic anomalies were detected prenatally or postnatally, 65 (62.6 %) cases were classified as idiopathic and recent TORCH positivity was not observed in any of the cases 0 (0%). Most cases were delivered at term (81.8%), median gestational week at delivery was 36 (range, 23-41), and the mean standard deviation birthweight was 2996±969 grams. Polyhydramnios was more common in male than in female fetuses (67% vs 33%). Termination of pregnancy was selected in 1 (0.9%) of the cases diagnosed with acrania and performed at 23 weeks of pregnancy with fetocide. There were 2 intrauterine fetal demise at 32 and 35 weeks of gestation diagnosed with Trisomy 18 and cardiac anomaly respectively. 101 (97.1 %) were live born and 29 of 101 live born infants were needed neonatal intensive care unit. Conclusion: Glucose tolerance test, detailed sonography, including fetal echocardiography should be performed in the pregnancies complicated with polyhydramnios. However, it is also reassuring for parents that the vast majority of cases are idiopathic.