Breaking the cycle: A comprehensive approach to treating recalcitrant nodulocystic acne in a young adult

This report presents a case of recalcitrant nodulocystic acne in a 25-year-old male patient with a two-year history of persistent, recurrent lesions. The patient was previously treated with various surgical techniques, including incision and drainage and excision, without sustained resolution. Upon presentation to our department, a multimodal approach was initiated, involving surgical drainage, intralesional injections, systemic antibiotics, and isotretinoin therapy. The treatment regimen led to a significant reduction in active lesions, with minimal residual scarring and no post-inflammatory pigmentation. The patient is currently on regular follow-up with no signs of recurrence.