Comparative Study of Hematological Parameters in Myeloproliferative Syndromes

Introduction Myeloproliferative syndromes, including conditions such as chronic myelogenous leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis, are characterized by the excessive production of stem cells in the bone marrow. This study aims to describe the epidemiological and cytological profile of these syndromes at the Mohammed V Military Instruction Hospital in Rabat. Materials and Methods: The study, conducted over one year, was observational, cross-sectional, descriptive, and analytical. Data were collected from the hematology laboratory registers, and statistical analysis was performed using IBM SPSS Statistics 19 and Microsoft Excel 2019.  Results Fourteen suspected cases of myeloproliferative syndrome were identified, with a male predominance (69.2%) and an average age of 57.75 years for CML, 61.75 years for PMF, 73 years for PV, and 81 years for ET. The main presentations included leukocytosis for CML, thrombocytosis for PV, and multilineage dysplasia for PMF.  Conclusion Our study at HMIMV Rabat highlights the importance of a multidisciplinary approach to myeloproliferative syndromes. Advanced hematological and cytological analysis methods were crucial for confirming the diagnosis and guiding treatment.

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Publication Details

Published
2025-03-22
DOI
https://doi.org/10.38124/ijisrt/25mar564
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
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Comparative Study of Hematological Parameters in Myeloproliferative Syndromes

A. Amri, D Talhik, H Zahid, Khadija Essahli et al.
Myeloproliferative Neoplasms: Diagnosis and Treatment
article

Comparative Study of Hematological Parameters in Myeloproliferative Syndromes

A. Amri, D Talhik, H Zahid, Khadija Essahli, A Hinda
article en

Abstract

Introduction Myeloproliferative syndromes, including conditions such as chronic myelogenous leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis, are characterized by the excessive production of stem cells in the bone marrow. This study aims to describe the epidemiological and cytological profile of these syndromes at the Mohammed V Military Instruction Hospital in Rabat. Materials and Methods: The study, conducted over one year, was observational, cross-sectional, descriptive, and analytical. Data were collected from the hematology laboratory registers, and statistical analysis was performed using IBM SPSS Statistics 19 and Microsoft Excel 2019.  Results Fourteen suspected cases of myeloproliferative syndrome were identified, with a male predominance (69.2%) and an average age of 57.75 years for CML, 61.75 years for PMF, 73 years for PV, and 81 years for ET. The main presentations included leukocytosis for CML, thrombocytosis for PV, and multilineage dysplasia for PMF.  Conclusion Our study at HMIMV Rabat highlights the importance of a multidisciplinary approach to myeloproliferative syndromes. Advanced hematological and cytological analysis methods were crucial for confirming the diagnosis and guiding treatment.

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Myeloproliferative Neoplasms: Diagnosis and Treatment
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