Synthesis and characterization of novel PIPERIDINYL-methyl-PURINEAMINE derivatives

Piperidinyl methyl purine amines are the biologically active compounds, which exhibit different biological activities; we here in reported the purine amine derivatives from bromo fluoro isonicotinate in six steps, which involves, Suzuki coupling, SNAr reaction with different amines, reduction, chlorination, regioselective substitution and deprotection reactions. All the compounds characterized by using 1 H NMR, 13 C NMR and mass spectral analysis.