Eplerenone, diabetes, and chronic kidney disease in patients hospitalized for acute heart failure: findings from the EARLIER trial
In patients with acute HF, the combination of diabetes and CKD was associated with an increased risk of cardiovascular events. However, the efficacy and safety of eplerenone were not influenced by diabetes and CKD status.
Authors
- Akira Yamashina
- Ayako Tezuka (ORCID: https://orcid.org/0000-0002-9978-2115)
- Ryu Takagi
- Masanori Asakura (ORCID: https://orcid.org/0000-0002-9872-671X)
- Masataka Watanabe
- Masatake Kobayashi (ORCID: https://orcid.org/0000-0003-0008-2256)
- Kazuhiro Satomi (ORCID: https://orcid.org/0000-0001-6858-8523)
- Masafumi Kitakaze
- Shin Ito
Institutions
- Tokyo Medical University (JP)
- National Cerebral and Cardiovascular Center (JP)
- Hanwa Memorial Hospital (JP)
- Hyogo University (JP)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1186/s12933-025-02659-y
- Citations
- 1
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.29