Silver‐Catalyzed Halochalcogenation of Terminal Alkynols to Access Halogenated Selenonaphthalenes
Herein, we report an AgNO<sub>3</sub> and FeCl<sub>3</sub> relay-catalyzed halogenation and electrophilic selenium cyclization reaction. This reaction is based on the trifunctionalization of terminal alkynols using NBS and diorganyl diselenides, providing a step-efficient synthetic approach to produce halogenated selenonaphthalene derivatives in good yields. Furthermore, the halochalcogenation and cyclization reaction offers an efficient protocol for constructing molecules with two independent reactive centers.
Authors
- Yibiao Li
- Huanliang Hong (ORCID: https://orcid.org/0000-0002-5680-8151)
- Sijie Xie
- Li Wang (ORCID: https://orcid.org/0000-0002-4658-2558)
Institutions
- Wuyi University (CN)
- Wuyi University (CN)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1002/chem.202500683
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.94