Hypersensitivity Reactions to Fibrin Glue during Epidural Blood Patching
We found a 0.49% incidence of hypersensitivity reactions during EBP with fibrin glue, none occurring during the first exposure. Younger age, lower BMI, and inadvertent intravenous injection during the procedure were associated with a higher likelihood of reactions. This study provides data useful for counseling patients on procedural risk and identifies variables for physicians to be aware of to help prevent life-threatening reactions to fibrin glue during EBP.
Authors
- Michael D. Malinzak (ORCID: https://orcid.org/0000-0002-6007-6520)
- Myoung Joon Kim
- Alaattin Erkanli
- Samantha Morrison (ORCID: https://orcid.org/0000-0003-0787-8505)
- Timothy J. Amrhein (ORCID: https://orcid.org/0000-0002-9354-9486)
- Jennifer L. Smith (ORCID: https://orcid.org/0000-0002-0398-2121)
- Linda Gray (ORCID: https://orcid.org/0000-0001-5947-9552)
- Peter George Kranz (ORCID: https://orcid.org/0000-0001-5410-7135)
- Amy Stallings
Institutions
- Duke University (US)
- Duke Medical Center (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3174/ajnr.a8568
- Citations
- 2
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.78