Eighteen-Year Longitudinal Study of Uncomplicated and Complex Acute Otitis Media During the Pneumococcal Conjugate Vaccine Era, 2006–2023
The risk factors for developing cAOM compared to uAOM are similar. PCV13 significantly reduced cAOM and penicillin nonsusceptibility associated with S pneumoniae, driven by reduction in cases caused by serotype 19A. Haemophilus influenzae continued to be a dominant cause of cAOM. Although non-PCV13 S pneumoniae serotypes emerged in the late PCV13 era, the lower level of cAOM caused by S pneumoniae was sustained.
Authors
- Michael E. Pichichero (ORCID: https://orcid.org/0000-0002-8276-3938)
- Lindsay R. Grant (ORCID: https://orcid.org/0000-0002-4538-6424)
- Adriano Arguedas (ORCID: https://orcid.org/0000-0002-1659-8225)
- Frank N. Salamone
- Liz Wang
- Eduardo Gonzalez
- Naoko Fuji
- Mohammad Ali (ORCID: https://orcid.org/0000-0003-1410-388X)
- Peter Bajorski (ORCID: https://orcid.org/0000-0003-4213-7307)
- Ravinder Kaur (ORCID: https://orcid.org/0000-0001-6539-5339)
- Ashley Miller (ORCID: https://orcid.org/0000-0002-9754-9731)
Institutions
- Rochester Institute of Technology (US)
- Pfizer (United States) (US)
- Rochester General Hospital (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1093/infdis/jiaf154
- Citations
- 5
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 9.24