The correlation between complete blood cell and depression in binge-drinking population

Globally, depression remains the primary cause of both mental and physical disabilities, significantly contributing to the overall burden of disease worldwide. Complete blood cells, readily accessible in clinical settings and primary care clinics, serve as a valuable indicator for assessing mental health. If complete blood cell markers are indicative of depression in binge-drinking population, it can be a handy tool in primary care outpatient clinics and alcohol withdrawal organzations, with important public health implications for early screening, early detection, and early treatment of depression. The primary objective of this research is to explore the association between levels of complete blood cells and reported depression levels in individuals who exhibit binge-drinking behaviors. By exploring the data from the National Health and Nutrition Examination Survey database, the study population was divided into the binge-drinking population (n=581), and non-binge-drinking population (n=1163) and the depression scores were calculated based on Patient Health Questionnaire-9 (Using answer choices of "not at all," "a few days," " more than half of the days" and "almost every day", with corresponding values of 0, 1, 2, and 3, respectively. The total score of the nine questions indicates the level of depression.) The complete blood cell data was measured by the DxH 800 system, it produces the dataplot displays for visual representation of the differential, NRBC membership (types of cells), and concentration. In a one-way analysis of variance study conducted in Avona with a sample population of binge-drinkers, significant associations were observed between depression score and white blood cell count (WBC), mean cell hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), as well as gender and marital status (P<0.05). In multifactorial analysis, with binge drinkers as the sample population, WBC and gender were significantly associated with depression scores (P<0.05). When the sample population was altered to individuals who do not engage in binge-drinking, gender remained statistically significant, but the effect of WBC was not statistically significant, leading us to conclude that WBC levels in individuals with binge-drinking habits may be linked to depression.