Investigating the Effect of Reducing the Signs and Symptoms of Lid Wiper Epitheliopathy in Patients With Dry Eye Disease With Perfluorohexyloctane
Perfluorohexyloctane significantly reduced LWE and improved dry eye symptoms compared with no treatment, suggesting that PFHO may enhance ocular lubrication and reduce friction-related damage. Masked, randomized, trials are still needed to compare PFHO to other treatments in participants with LWE to support generalizability of results. ClinicalTrials.gov study NCT06671041.
Authors
- Stephen M. Montaquila
- Brad Giedd
- Gina Wesley
- Andrew D. Pucker (ORCID: https://orcid.org/0000-0003-4032-2744)
- Marta Vianya-Estopà (ORCID: https://orcid.org/0000-0001-5913-0764)
- Quentin X. Franklin
- Christopher Lievens (ORCID: https://orcid.org/0000-0003-4208-6175)
- John E. Meyers
- Morgan Bromley
- Zackarias Coker
Institutions
- Georgia College & State University (US)
- Southern College of Optometry (US)
- University of Alabama at Birmingham (US)
- Neurology Associates (US)
- Eye Care Associates (US)
- Complete Eye Care of Medina (US)
- Pittsburg State University (US)
- Anglia Ruskin University (GB)
Publication Details
- Journal
- Current Therapeutic Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.curtheres.2025.100786
- Citations
- 1
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.88