Time-of-flight-resolved interferometric speckle contrast optical spectroscopy (TOF-resolved iSCOS) (Conference Presentation)

We demonstrate the time-of-flight (TOF)-resolved interferometric speckle contrast optical spectroscopy (TOF-resolved iSCOS), which we implemented using a rapidly tunable laser and an ultrafast two-dimensional camera operating at 1.1 million frames per second. The wavelength-resolved camera frames are added to mimic the multi-exposure acquisitions, from which we achieve the time-of-flight resolved speckle contrast. This enables us to estimate the depth-dependent blood flow index to monitor the human blood flow in vivo at short source-collector separations.