NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization

Our findings highlight the critical role of NSUN5 in CCA progression through m5C-dependent stabilization of the GLS transcript, suggesting a potential targeted therapeutic strategy for CCA.

Authors

Institutions

Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2025-03-20
DOI
https://doi.org/10.1007/s00432-025-06163-4
Citations
6
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
4.84
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization

Yikai Huang, Ming Shu, Kun‐Peng Guo, Weishan Wang
6 citations
Journal of Cancer Research and Clinical Oncology
RNA modifications and cancer
4.84
article

NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization

Yikai Huang, Ming Shu, Kun‐Peng Guo, Weishan Wang
article en
6 citations

Abstract

Our findings highlight the critical role of NSUN5 in CCA progression through m5C-dependent stabilization of the GLS transcript, suggesting a potential targeted therapeutic strategy for CCA.

Journal of Cancer Research and Clinical OncologyVol. 151(3)
Shanghai Electric (China) (CN)
Zero hunger
Openalex Percentile: Top 5%
RNA modifications and cancer
4.84
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization — Yikai Huang, Ming Shu, et al. · Journal of Cancer Research and Clinical Oncology (2025) | TGRS Research Map | TGRS