Condition-controlled selective synthesis of spiroisoquinolinones or spiroisoindolinones <i>via</i> CHA–initiated spiroannulation, ring opening and ring contraction
Presented herein is a condition-controlled selective synthesis of isoindole spiroisoquinolinone or isoindole spiroisoindolinone derivatives based on the cascade reactions of 3-phenylisoxazolone with diazo homophthalimide.
Authors
- Shuya Zhang (ORCID: https://orcid.org/0000-0001-6002-2576)
- Xuesen Fan (ORCID: https://orcid.org/0000-0002-2040-6919)
- Xinying Zhang (ORCID: https://orcid.org/0000-0001-7092-9446)
- Yuanshuang Xu
- Yujing Xiao
Institutions
- Henan Normal University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00257e
- Citations
- 6
- Primary Topic
- Synthesis and pharmacology of benzodiazepine derivatives
- Type
- article
- Field-Weighted Citation Impact
- 5.62