Targeted Prostate Biopsies Overestimate International Society of Urological Pathology Grade Group, Particularly in Smaller Tumors
In this report, we examined risk factors that could explain why some patients have higher pathological grading at prostate biopsy than on the whole prostate specimen after surgical removal. We found that patients with prostate biopsies that are targeted at small lesions on magnetic resonance imaging and patients who had high biopsy grading had a higher risk of having lower grading of their surgical specimens.
Authors
- Lisa J Kroon (ORCID: https://orcid.org/0009-0003-6801-3633)
- Monique J. Roobol (ORCID: https://orcid.org/0000-0001-6967-1708)
- Charlotte F. Kweldam (ORCID: https://orcid.org/0000-0002-1581-9612)
- Roderick C.N. van den Bergh
- Ivo I. de Vos (ORCID: https://orcid.org/0000-0001-9000-7457)
- Geert J.L.H. van Leenders (ORCID: https://orcid.org/0000-0003-2176-9102)
Institutions
- Maasstad Ziekenhuis (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- European Urology Open Science
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1016/j.euros.2025.02.008
- Citations
- 1
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Jaap Schouten Foundation