Recombinant high-density lipoprotein targeted delivery of celastrol to promote foam cells lipophagy against early atherosclerosis
A combination of hypolipidemic chemo-intervention with rHDL participated specific and reverse delivery may offer a promising strategy for biocompatible treatment of early atherosclerosis.
Authors
- Cheng-Wei Lü (ORCID: https://orcid.org/0000-0002-2217-3231)
- Jue Yang
- Tian Meng (ORCID: https://orcid.org/0000-0003-2115-5848)
- Yuanyan Liu (ORCID: https://orcid.org/0000-0003-3840-5292)
- Xiao Cheng (ORCID: https://orcid.org/0000-0002-6602-7463)
- Li Yang (ORCID: https://orcid.org/0000-0001-6589-7195)
- Xiaoyu Li (ORCID: https://orcid.org/0000-0002-5618-8888)
- Jinxiu Qian
- Xiaoxia Xue
- Liuchunyang Yu
- Rongjun Deng (ORCID: https://orcid.org/0000-0003-3545-9340)
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1186/s12951-025-03327-9
- Citations
- 8
- Primary Topic
- Nuclear Receptors and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 7.27
Funders
- National Natural Science Foundation of China