Revolutionary MRI Imaging for Alzheimer's: Cutting-Edge GANs and Vision Transformer Solutions

This study introduces a new approach to diagnosing Alzheimer’s disease by combining Generative Adversarial Networks (GANs) with Vision Transformers (ViTs) to tackle the common issue of limited medical imaging data. GANs are used to generate synthetic MRI images of Alzheimer’s patients, which are combined with real images to create a richer and more varied dataset. In this approach, the GAN model— comprising a generator and discriminator—learns to produce high-quality synthetic MRI images that, together with real data, significantly expand the training set. These images are then fed into a ViT model, which, thanks to its self-attention mechanisms, excels at identifying and classifying the stages of Alzheimer’s disease. Our evaluation shows impressive results, with metrics including accuracy, F1-score, AUC, precision, and recall reaching 98.8%, 98.43%, 99.5%, 98%, and 98%, respectively— showing the effectiveness of the expanded dataset in boosting classification performance. This integrated GAN-ViT approach not only enhances diagnostic accuracy for Alzheimer’s but also sets the stage for applying similar techniques across other medical imaging domains, providing better tools for understanding disease progression and improving patient outcomes.

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Publication Details

Published
2025-01-09
DOI
https://doi.org/10.1109/ipas63548.2025.10924560
Primary Topic
Brain Tumor Detection and Classification
Type
article
Field-Weighted Citation Impact
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article

Revolutionary MRI Imaging for Alzheimer's: Cutting-Edge GANs and Vision Transformer Solutions

Mounir Sayadi, Houmem Slimi, Sabeur Abid, Imen Cherif
Brain Tumor Detection and Classification
article

Revolutionary MRI Imaging for Alzheimer's: Cutting-Edge GANs and Vision Transformer Solutions

Mounir Sayadi, Houmem Slimi, Sabeur Abid, Imen Cherif
article en

Abstract

This study introduces a new approach to diagnosing Alzheimer’s disease by combining Generative Adversarial Networks (GANs) with Vision Transformers (ViTs) to tackle the common issue of limited medical imaging data. GANs are used to generate synthetic MRI images of Alzheimer’s patients, which are combined with real images to create a richer and more varied dataset. In this approach, the GAN model— comprising a generator and discriminator—learns to produce high-quality synthetic MRI images that, together with real data, significantly expand the training set. These images are then fed into a ViT model, which, thanks to its self-attention mechanisms, excels at identifying and classifying the stages of Alzheimer’s disease. Our evaluation shows impressive results, with metrics including accuracy, F1-score, AUC, precision, and recall reaching 98.8%, 98.43%, 99.5%, 98%, and 98%, respectively— showing the effectiveness of the expanded dataset in boosting classification performance. This integrated GAN-ViT approach not only enhances diagnostic accuracy for Alzheimer’s but also sets the stage for applying similar techniques across other medical imaging domains, providing better tools for understanding disease progression and improving patient outcomes.

Tunis University (TN)
Openalex Percentile: Top 93%
Brain Tumor Detection and Classification
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Revolutionary MRI Imaging for Alzheimer's: Cutting-Edge GANs and Vision Transformer Solutions — Mounir Sayadi, Houmem Slimi, et al. · (2025) | TGRS Research Map | TGRS