Effects of breast size on breast reconstruction in BRCA mutation carriers and genetic high-risk patients after bilateral mastectomy

The preoperative breast size of gene mutation carriers influences the postmastectomy reconstructive choice. TMG and SGAP flaps are suitable options for bilateral reconstruction of genetic susceptible patients with small breasts, while DIEP flaps are preferred in larger breast sizes. With increasing breast size an elevated risk for elective revisions after either IBR or ABR need to be considered. Women with medium-to-large breasts exhibit increased morbidity related to expansion and genetic high-risk patients may benefit from prior reduction mammoplasty.

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Publication Details

Journal
Breast Cancer
Published
2025-03-20
DOI
https://doi.org/10.1007/s12282-025-01691-w
Primary Topic
Breast Implant and Reconstruction
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of breast size on breast reconstruction in BRCA mutation carriers and genetic high-risk patients after bilateral mastectomy

Sonia Fertsch, Vendela Grufman, Nicole E. Speck, Jian Farhadi et al.
Breast Cancer
Breast Implant and Reconstruction
article

Effects of breast size on breast reconstruction in BRCA mutation carriers and genetic high-risk patients after bilateral mastectomy

Sonia Fertsch, Vendela Grufman, Nicole E. Speck, Jian Farhadi, Martin C. Lam, Florian Recker
article en

Abstract

The preoperative breast size of gene mutation carriers influences the postmastectomy reconstructive choice. TMG and SGAP flaps are suitable options for bilateral reconstruction of genetic susceptible patients with small breasts, while DIEP flaps are preferred in larger breast sizes. With increasing breast size an elevated risk for elective revisions after either IBR or ABR need to be considered. Women with medium-to-large breasts exhibit increased morbidity related to expansion and genetic high-risk patients may benefit from prior reduction mammoplasty.

Breast CancerVol. 32(3)
University of Bonn (DE), Witten/Herdecke University (DE), University of Basel (CH), University Hospital Bonn (DE), Martin University (US), University Hospital of Basel (CH), Sana Kliniken AG (DE)
Good health and well-being
Openalex Percentile: Top 91%
Breast Implant and Reconstruction
DOIOpen Access PDFOpenAlex
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Effects of breast size on breast reconstruction in BRCA mutation carriers and genetic high-risk patients after bilateral mastectomy — Sonia Fertsch, Vendela Grufman, et al. · Breast Cancer (2025) | TGRS Research Map | TGRS