Smartphone-enabled devices for dynamic analysis of biofluid samples at the point of care (Conference Presentation)

Advances in point-of-care diagnostic devices are essential to lower the fabrication cost and make them more accessible, especially for underserved populations. In this talk, I will present the most recent findings from our research, focusing on the research on the development of optical technologies that use the advantages of 3D printing and low-cost microfluidic chip fabrication. The technologies do not require any specific brand of smartphone and external optical components to perform the specific measurement at the point of care with high accuracy. A 3D-printed casing integrated with illumination sources and a low-cost sample cartridge are required for the smartphone-enabled measurement. The acquired data is processed using our custom-developed algorithms. Each platform costs less than $10 and does not require expertise to perform the measurements. We evaluated and validated the performances of our platforms using lab-prepared samples, commercially available products, and clinical samples. These cost-effective platforms, demonstrating an excellent agreement with the results obtained from equivalent gold standard methods, can help analyze the dynamics of samples at POC.