Towards drug delivery systems triggered by ion-selective interactions
A drug delivery system is proposed that allows the release of a drug from a lipophilic polymer in response to ion-selective interactions with trigger ions present in solution. Spontaneous and stoichiometric incorporation of the trigger ions into a polymer phase is driven by their preferential binding to an uncharged ionophore resulting in charged drug ions being released to preserve electroneutrality.
Authors
- Dorota Buczyńska (ORCID: https://orcid.org/0000-0003-1030-078X)
- Justyna Kalisz (ORCID: https://orcid.org/0000-0002-4188-5074)
- Piotr Piątek (ORCID: https://orcid.org/0000-0003-0374-5561)
- Emilia Stelmach (ORCID: https://orcid.org/0000-0003-1565-4819)
- Agata Michalska (ORCID: https://orcid.org/0000-0002-8509-1428)
- Krzysztof Maksymiuk (ORCID: https://orcid.org/0000-0002-3931-3798)
- Bohdan Paterczyk (ORCID: https://orcid.org/0000-0002-6918-2688)
Institutions
- University of Warsaw (PL)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00636h
- Citations
- 4
- Primary Topic
- Analytical Chemistry and Chromatography
- Type
- article
- Field-Weighted Citation Impact
- 3.03