The investigation of blood flow-induced uncertainty in the measurement of birefringent properties using polarization sensitive OCT (Conference Presentation)

The framework presented in this study demonstrates that blood flow with tissue induces substantial uncertainty in polarization-sensitive optical coherence tomography imaging. By extracting the static components through Eigen decomposition, the impact of dynamic blood flow on the polarization measurements of the underlying sample can be minimized. Our phantom study shows that this method significantly reduces the effect of overlying blood flow on measuring the birefringent properties of the underlying sample. We further validate this approach through in vivo imaging of the human nail fold.