Evaluation of laser ablation-induced thermal damage by computational simulation of light and heat transfer in tissue with dynamic optical properties model (Conference Presentation)

This study presents a computational simulation of light and heat transfer in tissue with a dynamic optical properties model. The simulation model was validated by performing optical property measurements and irradiation experiments on porcine liver tissue. Comparison of the simulation results with the experimental results showed that the proposed simulation calculated the photothermal damage area, which was defined as the sum of the coagulation and vaporization areas, with 2.3 times higher accuracy than conventional simulations. Our results demonstrate the improvement of a laser ablation simulation by considering dynamic optical properties and may be useful for retrospective evaluation of laser ablation.

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Publication Details

Published
2025-03-20
DOI
https://doi.org/10.1117/12.3040327
Primary Topic
Ocular and Laser Science Research
Type
article
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article

Evaluation of laser ablation-induced thermal damage by computational simulation of light and heat transfer in tissue with dynamic optical properties model (Conference Presentation)

Toshiyuki Ozawa, Daisuke Tsuruta, Yu Shimojo, Takahiro Nishimura
Ocular and Laser Science Research
article

Evaluation of laser ablation-induced thermal damage by computational simulation of light and heat transfer in tissue with dynamic optical properties model (Conference Presentation)

Toshiyuki Ozawa, Daisuke Tsuruta, Yu Shimojo, Takahiro Nishimura
article en

Abstract

This study presents a computational simulation of light and heat transfer in tissue with a dynamic optical properties model. The simulation model was validated by performing optical property measurements and irradiation experiments on porcine liver tissue. Comparison of the simulation results with the experimental results showed that the proposed simulation calculated the photothermal damage area, which was defined as the sum of the coagulation and vaporization areas, with 2.3 times higher accuracy than conventional simulations. Our results demonstrate the improvement of a laser ablation simulation by considering dynamic optical properties and may be useful for retrospective evaluation of laser ablation.

Osaka Metropolitan University (JP), Tokyo Metropolitan University (JP), The University of Osaka (JP)
Openalex Percentile: Top 90%
Ocular and Laser Science Research
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Evaluation of laser ablation-induced thermal damage by computational simulation of light and heat transfer in tissue with dynamic optical properties model (Conference Presentation) — Toshiyuki Ozawa, Daisuke Tsuruta, et al. · (2025) | TGRS Research Map | TGRS