OLANZAPINE AS A FIRST LINE OF CHOICE IN POSTPARTUM PSYCHOSIS – A CASE SERIES

Postpartum psychosis is a severe, acute, mental illness of multifactorial origin showing hallucinations, delusions and disorganized thoughts. Risk factors include bipolar affect, depression, traumatic childhood, primigravida, higher daily cortisol levels, rst born women, dysregulation of immune-HPA axis along with stress, use of psychoactive drugs, risk of hospital admission, lack of sleep, rapidly falling estrogen levels and environmental as well as social factors. Positive and Negative Syndrome Scale (PANSS) along with Clinical Global Impressions (CGI) were used for diagnosis and prognosis during the course of treatment. It warrants urgency since the condition poses a threat to both maternal and natal health. Timely measures ensure well-being of both the mother and the child and thus the whole family. We study 3 postpartum psychosis cases in this series, where all showed different symptoms and were treated with Olanzapine which is amongst the rst line drugs of choice. All 3 showed good prognosis with marked symptomatic relief, thus strengthening the evidence of Olanzapine as a rst line drug of choice in postpartum psychosis.