An Update on Natural Remedies for Calciphylaxis in Home Managemen

Calciphylaxis is a progressive inflammatory disease that affects small and medium-sized arteries, where calcification leads to thrombotic ischemia.This ischemia manifests as painful nodules, plaques, or necrotic ulcerations on the skin.While most commonly seen in patients with end-stage renal disease (ESRD), calciphylaxis can also occur in individuals with acute kidney injury or even in those without any known renal disease.With a one-year mortality rate as high as 50%, calciphylaxis is challenging to diagnose and treat due to its systemic effects and highly variable clinical presentation [1].The appearance of calciphylaxis lesions depends on the stage of the disease, the patient's skin tone, and the anatomical location of the affected area.Early on, lesions can range from subcutaneous nodules without epidermal changes to retiform purpura or branching purpuric plaques and patches.As